I am not sure exactly what “series” you are talking about…
But I do know of something very similar that happened in reality.
This guy I once knew, Rand…had almost the exact same thing happen to him…
However, I have no idea what mana corruption would be, there isn’t an anti-mana.
HOWEVER, Tom does mention the fact that the mana from Tiernon is extra pure, concentrated almost.
So, one might assume that gods filter the mana, or there is some sort of mana filtration system on the stuff going into the pool. (This is actually the Illuminary System as described in Book II)
So…I would think, even if one could figure out how to contaminate said mana pool, the deity or his/her avatars could just refilter it.
Or, maybe use it as is, sort of like bad gasoline. Some engines might get choked up on it, others could run on it…